Histamine phosphate

Histamine phosphate Basic information Product Name: Histamine phosphate Synonyms: HISTAMINEPHOSPHATE,USP;2-(4-Imidazolyl)ethylamine diphosphate salt, 2-(4-Imidazolyl)ethylamine monohydrate diphosphate salt, Histamine monohydrate diphosphate salt;2-(4-Imidazolyl)ethylamine diphosphate salt monohydrate;Histamine diphosphate salt monohydrat;Histamine bisphosphate monohydrate,2-(4-Imidazolyl)ethylamine diphosphate salt monohydrate, 2-(4-Imidazolyl)ethylamine diphosphate salt, Histamine diphosphate salt monohydrate;Histamine diphosphat;Histapon;HistaMine Diphosphate  CAS: 51-74-1 MF: C5H12N3O4P MW: 209.14 EINECS: 200-118-4 Product Categories: Other APIs;Inhibitors Mol File: 51-74-1.mol… ادامه خواندن Histamine phosphate

Betulin

Betulin Basic information Extract Physical and Chemical Properties Extraction method Identification method Physiological functions Storage References Product Name: Betulin Synonyms: Lup-20(29)-ene-3,28-diol, (3β)-;BETULIN(P);BETULIN hplc;Betulin,Betulinol,Betulol,Betulenol;3b,28-Dihydroxylup-20(29)-ene;Betulinic alcohol;SpirulinaPowder&Tablets;etulin CAS: 473-98-3 MF: C30H50O2 MW: 442.72 EINECS: 207-475-5 Product Categories: Triterpenoids;Tri-Terpenoids;natural product;Pentacyclic Triterpenes;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;473-98-3 Mol File: 473-98-3.mol Betulin Chemical Properties Melting point  256-257 °C(lit.) alpha  D15 +20° (c =… ادامه خواندن Betulin

Betulin

Betulin Basic information Extract Physical and Chemical Properties Extraction method Identification method Physiological functions Storage References Product Name: Betulin Synonyms: Lup-20(29)-ene-3,28-diol, (3β)-;BETULIN(P);BETULIN hplc;Betulin,Betulinol,Betulol,Betulenol;3b,28-Dihydroxylup-20(29)-ene;Betulinic alcohol;SpirulinaPowder&Tablets;etulin CAS: 473-98-3 MF: C30H50O2 MW: 442.72 EINECS: 207-475-5 Product Categories: Triterpenoids;Tri-Terpenoids;natural product;Pentacyclic Triterpenes;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;473-98-3 Mol File: 473-98-3.mol Betulin Chemical Properties Melting point  256-257 °C(lit.) alpha  D15 +20° (c =… ادامه خواندن Betulin

Triclabendazole

Triclabendazole Basic information Product Name: Triclabendazole Synonyms: FASINEX;CGA-89317;5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-1H-BENZIMIDAZOLE;TRICLABENDAZOLE;5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1h-benzimidazol;5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthio-1H-benzimidazole, CGA-89317, Fasinex;1H-Benzimidazole, 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-;5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-(METHYLTHIO)-1H-BENZIMIDAZOL(TRICLABENDAZOLE) CAS: 68786-66-3 MF: C14H9Cl3N2OS MW: 359.66 EINECS: 614-728-7 Product Categories: Veterinary drugs;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;API’s;Pharmaceutical intermediate;68786-66-3 Mol File: 68786-66-3.mol Triclabendazole Chemical Properties Melting point  175-176°C Boiling point  240.6°C (rough estimate) density  1.3875 (rough estimate) refractive index  1.6000 (estimate) storage temp.  Sealed in dry,Room Temperature… ادامه خواندن Triclabendazole

Apremilast

Apremilast Basic information Description Uses Metabolism and Drug interaction safety information side effects References Product Name: Apremilast Synonyms: (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide;ApreMilast,CC-10004;AcetaMide, N-[2-[(1S)-1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Apremilast (CC-10004;(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl);Apremilast (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione;Appleton West;N-[2-[(1S)-1-(3ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide CAS: 608141-41-9 MF: C22H24N2O7S MW: 460.5 EINECS: 807-237-6 Product Categories: Other series;Inhibitors;Inhibitor;GS;API Mol File: 608141-41-9.mol Apremilast Chemical Properties Melting point  152-156°C Boiling point  741.3±60.0 °C(Predicted) density  1.381 storage temp.  Refrigerator solubility  Chloroform (Slightly), DMSO (Slightly), Methanol… ادامه خواندن Apremilast

Carfilzomib

Carfilzomib Basic information description Mechanism Side effects Efficacy and Safety Product Name: Carfilzomib Synonyms: CarfilzoMib salt;CarfilzoMib/PR 171;PR 171;PR-171 (CarfilzoMib);(alphaS)-alpha-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-phenylalaninamide;Carfilzomib;CarfilzoMib, Free Base, >99%;(S)-4-Methyl-N-((S)-1-((S)-4-Methyl-1-((R)-2- Methyloxiran-2-yl)-1 -oxopentan-2-ylaMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide CAS: 868540-17-4 MF: C40H57N5O7 MW: 719.92 EINECS: 692-054-2 Product Categories: Inhibitors;peptides;API;Inhibitor;Pharmaceutical;868540-17-4 Mol File: 868540-17-4.mol Carfilzomib Chemical Properties Melting point  204 – 208°C Boiling point  975.6±65.0 °C(Predicted) density  1.161 Fp  543.8℃ storage temp.  -20° solubility … ادامه خواندن Carfilzomib

Ponatinib

Ponatinib Basic information Anticancer drug Pharmacological effects Toxic side effect Standard dose Drug Interactions Drug contraindications Product Name: Ponatinib Synonyms: AP24534(Ponatinib);3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide;AP24534;AP24534;PONATINIB;3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-(4-((4-METHYLPIPERAZIN-1-YL)METHYL)-3-(TRIFLUOROMETHYL)PHENYL)BENZAMIDE;Ponatinib;3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide;Ponatinib (AP24534);Ponatinib (with 4 ints.) CAS: 943319-70-8 MF: C29H27F3N6O MW: 532.56 EINECS: 1308068-626-2 Product Categories: Inhibitors;Pharmaceuticals;Tyrosine Kinase Inhibitors;Potent multi-kinase and pan-BCR-ABL inhibitor.;Heterocycles;Intermediates & Fine Chemicals;API;943319-70-8 Mol File: 943319-70-8.mol Ponatinib Chemical Properties Melting point  >175°C (dec.) density  1.3 storage temp.  -20°C… ادامه خواندن Ponatinib

Lenvatinib

Lenvatinib Basic information Thyroid cancer drugs Biological activity In vitro study In vivo studies Feature Product Name: Lenvatinib Synonyms: 4-[3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinolinecarboxamide;E7080 (Lenvatinib);ER-203492-00;1-(4-(6-carbamoyl-7-methoxyquinolin-4-yloxy)-2-chlorophenyl)-3-cyclopropylurea;4-[3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinolinecarboxamide XEN445;E70801-(4-(6-carbamoyl-7-methoxyquinolin-4-yloxy)-2-chlorophenyl)-3-cyclopropylurea;4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide methanesulfonate;LENVATINIB CAS: 417716-92-8 MF: C21H19ClN4O4 MW: 426.85 EINECS: 1592732-453-0 Product Categories: Inhibitors;FGF receptor antagonist;API;417716-92-8;Intermediate Mol File: 417716-92-8.mol Lenvatinib Chemical Properties Melting point  >216°C (dec.) Boiling point  627.2±55.0 °C(Predicted) density  1.46 storage temp.  -20°C solubility  Soluble in DMSO… ادامه خواندن Lenvatinib

ONDANSETRON HYDROCHLORIDE

ONDANSETRON HYDROCHLORIDE Basic information Product Name: ONDANSETRON HYDROCHLORIDE Synonyms: sn307;thyl)-,hydrochloride,hydrate(1:1:2);1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one hydrochloride dihydrate;4H-Carbazol-4-one,1,2,3,9-tetrahydro-9-Methyl-3-[(2-Methyl-1H-iMidazol-1-yl)Methyl]-,hydrochloride (1:1);1,2,3,9-Tetrahydro-9-Methyl-3-[(2-Methyl-1H-iMidazol-1-yl)Methyl]-4H-carbazol-4-one Hydochloride;EMeset;Osetron;Paroxetine EP IMpurity A CAS: 99614-01-4 MF: C18H20ClN3O MW: 329.82 EINECS: Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Serotonin receptor;Amines;Heterocycles;Inhibitors Mol File: 99614-01-4.mol ONDANSETRON HYDROCHLORIDE Chemical Properties Melting point  178.5-179.5°C storage temp.  Inert atmosphere,Store in freezer, under -20°C solubility  H2O: >5 mg/mL pka… ادامه خواندن ONDANSETRON HYDROCHLORIDE

LY 294002 HYDROCHLORIDE

LY 294002 HYDROCHLORIDE Basic information Product Name: LY 294002 HYDROCHLORIDE Synonyms: LY 294002;LY 294002 HYDROCHLORIDE;2-[4-MORPHOLINYL]-8-PHENYL-1[4H]-BENZOPYRAN-4-ONE;2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE;2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE HYDROCHLORIDE;2-(4-MORPHOLINO)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE;LY 294002, 99+%;LY294002HCl CAS: 154447-36-6 MF: C19H17NO3 MW: 307.34 EINECS: 1312995-182-4 Product Categories: Inhibitors;Inhibitor;Anti-cancer&immunity;PI3K/Akt/mTOR;Akt;mTOR;PI3K;Cell Cycle Regulation;apis;Signalling;Lipid signaling;PI3K/Akt Signaling Mol File: 154447-36-6.mol LY 294002 HYDROCHLORIDE Chemical Properties Melting point  183-185℃ Boiling point  494.6±45.0 °C(Predicted) density  1.266 storage temp.  Sealed in dry,Store… ادامه خواندن LY 294002 HYDROCHLORIDE