دسته: مهندسی بیوشیمی

Aconitine Basic information Product Name: Aconitine Synonyms: (1ALPHA,3ALPHA,6ALPHA,14ALPHA,15ALPHA,16BETA)-20-ETHYL-1,6,16-TRIMETHOXY-4-(METHOXYMETHYL)ACONITANE-3,8,13,14,15-PENTOL 8-ACETATE 14-BENZOATE;2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine-4,8,9,11,11a(1H,7H)-pentol, 1-ethyldecahydro-6,10,13-trimethoxy-3-(methoxymethyl)-, 11a-acetate 8-benzoate;Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1a,3a,6a,14a,15a,16b)-;Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-;20-Ethyl-1α,6α,16β-trimethoxy-14α-benzoyloxy-4-(methoxymethyl)aconitane-3α,8,13,15α-tetrol 8-acetate;20-Ethyl-1α,6α,16β-trimethoxy-4-(methoxymethyl)aconitane-3α,8,13,14α,15α-pentol 8-acetate 14-benzoate;(1ALPHA,3ALPHA,6ALPHA,14ALPHA,15ALPHA,16BETA)-20-ETHYL-1,6,16-TRIMETHOXY-4-(METHOXYMETHYL)ACONITANE-3,8,13,14,15-PENTOL 8-ACETATE 14-BENZOATE;ACONITANE-3,8,13,14,15-PENTOL,20-ETHYL-1,6,16-TRIMETHOXY-4-(MET CAS: 302-27-2 MF: C34H47NO11 MW: 645.74 EINECS: 206-121-7 Product Categories: Alkaloids;Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Amines, Aromatics, Chiral Reagents, Pharmaceuticals,… ادامه خواندن Aconitine

Clopidogrel Bisulfate Basic information Product Name: Clopidogrel Bisulfate Synonyms: Clopidogrel Hydrogen Shlfate;Iscover;Clopidogrel (as bisulphate);Methyl (S)-(+)-2-(2-Chlorophenyl)-2-[6,7-dihydro-4H-thieno[3;d-Clopidogrel;(S)-alpha-(2-Chlorophenyl)-6,7-dihydrothieno[3.2-c]pyridine-5(4H)-aceticacidmethylesterhydrogensulfate;Clopidogrelhydrogenesulfate;(S)-METHYL-(2-CHLORO-PHENYL)-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETATE H2SO4 CAS: 120202-66-6 MF: C16H16ClNO2S.H2O4S MW: 419.9 EINECS: 1806241-263-5 Product Categories: APIs;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Clopidogrel;Cardiovascular Series;Pharmaceutical intermediates;Iscover;Cardiovascular APIs;INTERMEDIATES OF CLOPIDOGREL;API;120202-66-6 Mol File: 120202-66-6.mol Clopidogrel Bisulfate Chemical Properties Melting point  174-176°C storage temp.  2-8°C solubility  DMSO: ~26 mg/mL… ادامه خواندن Clopidogrel Bisulfate

3-AMINO-3-PHENYL-1-PROPANOL Basic information Product Name: 3-AMINO-3-PHENYL-1-PROPANOL Synonyms: RARECHEM AK ML 0271;3-AMINO-3-PHENYL-1-PROPANOL;3-AMINO-3-PHENYL-PROPAN-1-OL;DL-BETA-PHENYLALANINOL;3-amino-3-phenyl-1-propano;1-Propanol, 3-amino-3-phenyl.;3-Amino-3-phenyl-1-propanol,94%;Benzenepropanol, g-aMino- CAS: 14593-04-5 MF: C9H13NO MW: 151.21 EINECS: 640-670-7 Product Categories: Mol File: 14593-04-5.mol 3-AMINO-3-PHENYL-1-PROPANOL Chemical Properties Melting point  70-77 °C Boiling point  134°C/4mmHg(lit.) density  1.0406 (rough estimate) refractive index  1.4755 (estimate) storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C… ادامه خواندن 3-AMINO-3-PHENYL-1-PROPANOL

Histamine phosphate Basic information Product Name: Histamine phosphate Synonyms: HISTAMINEPHOSPHATE,USP;2-(4-Imidazolyl)ethylamine diphosphate salt, 2-(4-Imidazolyl)ethylamine monohydrate diphosphate salt, Histamine monohydrate diphosphate salt;2-(4-Imidazolyl)ethylamine diphosphate salt monohydrate;Histamine diphosphate salt monohydrat;Histamine bisphosphate monohydrate,2-(4-Imidazolyl)ethylamine diphosphate salt monohydrate, 2-(4-Imidazolyl)ethylamine diphosphate salt, Histamine diphosphate salt monohydrate;Histamine diphosphat;Histapon;HistaMine Diphosphate  CAS: 51-74-1 MF: C5H12N3O4P MW: 209.14 EINECS: 200-118-4 Product Categories: Other APIs;Inhibitors Mol File: 51-74-1.mol… ادامه خواندن Histamine phosphate

Betulin Basic information Extract Physical and Chemical Properties Extraction method Identification method Physiological functions Storage References Product Name: Betulin Synonyms: Lup-20(29)-ene-3,28-diol, (3β)-;BETULIN(P);BETULIN hplc;Betulin，Betulinol，Betulol，Betulenol;3b,28-Dihydroxylup-20(29)-ene;Betulinic alcohol;SpirulinaPowder&Tablets;etulin CAS: 473-98-3 MF: C30H50O2 MW: 442.72 EINECS: 207-475-5 Product Categories: Triterpenoids;Tri-Terpenoids;natural product;Pentacyclic Triterpenes;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;473-98-3 Mol File: 473-98-3.mol Betulin Chemical Properties Melting point  256-257 °C(lit.) alpha  D15 +20° (c =… ادامه خواندن Betulin

Betulin Basic information Extract Physical and Chemical Properties Extraction method Identification method Physiological functions Storage References Product Name: Betulin Synonyms: Lup-20(29)-ene-3,28-diol, (3β)-;BETULIN(P);BETULIN hplc;Betulin，Betulinol，Betulol，Betulenol;3b,28-Dihydroxylup-20(29)-ene;Betulinic alcohol;SpirulinaPowder&Tablets;etulin CAS: 473-98-3 MF: C30H50O2 MW: 442.72 EINECS: 207-475-5 Product Categories: Triterpenoids;Tri-Terpenoids;natural product;Pentacyclic Triterpenes;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;473-98-3 Mol File: 473-98-3.mol Betulin Chemical Properties Melting point  256-257 °C(lit.) alpha  D15 +20° (c =… ادامه خواندن Betulin

Triclabendazole Basic information Product Name: Triclabendazole Synonyms: FASINEX;CGA-89317;5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-1H-BENZIMIDAZOLE;TRICLABENDAZOLE;5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1h-benzimidazol;5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthio-1H-benzimidazole, CGA-89317, Fasinex;1H-Benzimidazole, 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-;5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-(METHYLTHIO)-1H-BENZIMIDAZOL(TRICLABENDAZOLE) CAS: 68786-66-3 MF: C14H9Cl3N2OS MW: 359.66 EINECS: 614-728-7 Product Categories: Veterinary drugs;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;API’s;Pharmaceutical intermediate;68786-66-3 Mol File: 68786-66-3.mol Triclabendazole Chemical Properties Melting point  175-176°C Boiling point  240.6°C (rough estimate) density  1.3875 (rough estimate) refractive index  1.6000 (estimate) storage temp.  Sealed in dry,Room Temperature… ادامه خواندن Triclabendazole

Apremilast Basic information Description Uses Metabolism and Drug interaction safety information side effects References Product Name: Apremilast Synonyms: (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide;ApreMilast,CC-10004;AcetaMide, N-[2-[(1S)-1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Apremilast (CC-10004;(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl);Apremilast (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione;Appleton West;N-[2-[(1S)-1-(3ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide CAS: 608141-41-9 MF: C22H24N2O7S MW: 460.5 EINECS: 807-237-6 Product Categories: Other series;Inhibitors;Inhibitor;GS;API Mol File: 608141-41-9.mol Apremilast Chemical Properties Melting point  152-156°C Boiling point  741.3±60.0 °C(Predicted) density  1.381 storage temp.  Refrigerator solubility  Chloroform (Slightly), DMSO (Slightly), Methanol… ادامه خواندن Apremilast

Carfilzomib Basic information description Mechanism Side effects Efficacy and Safety Product Name: Carfilzomib Synonyms: CarfilzoMib salt;CarfilzoMib/PR 171;PR 171;PR-171 (CarfilzoMib);(alphaS)-alpha-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-phenylalaninamide;Carfilzomib;CarfilzoMib, Free Base, >99%;(S)-4-Methyl-N-((S)-1-((S)-4-Methyl-1-((R)-2- Methyloxiran-2-yl)-1 -oxopentan-2-ylaMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide CAS: 868540-17-4 MF: C40H57N5O7 MW: 719.92 EINECS: 692-054-2 Product Categories: Inhibitors;peptides;API;Inhibitor;Pharmaceutical;868540-17-4 Mol File: 868540-17-4.mol Carfilzomib Chemical Properties Melting point  204 – 208°C Boiling point  975.6±65.0 °C(Predicted) density  1.161 Fp  543.8℃ storage temp.  -20° solubility … ادامه خواندن Carfilzomib

Ponatinib Basic information Anticancer drug Pharmacological effects Toxic side effect Standard dose Drug Interactions Drug contraindications Product Name: Ponatinib Synonyms: AP24534(Ponatinib);3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide;AP24534;AP24534;PONATINIB;3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-(4-((4-METHYLPIPERAZIN-1-YL)METHYL)-3-(TRIFLUOROMETHYL)PHENYL)BENZAMIDE;Ponatinib;3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide;Ponatinib (AP24534);Ponatinib (with 4 ints.) CAS: 943319-70-8 MF: C29H27F3N6O MW: 532.56 EINECS: 1308068-626-2 Product Categories: Inhibitors;Pharmaceuticals;Tyrosine Kinase Inhibitors;Potent multi-kinase and pan-BCR-ABL inhibitor.;Heterocycles;Intermediates & Fine Chemicals;API;943319-70-8 Mol File: 943319-70-8.mol Ponatinib Chemical Properties Melting point  >175°C (dec.) density  1.3 storage temp.  -20°C… ادامه خواندن Ponatinib