دسته: مهندسی بیوشیمی

Secretin Basic information Structure Gene, mRNA, and precursor Synthesis and release Receptors Biological functions Clinical implications Product Name: Secretin Synonyms: Secretine;Secretin-Kabi;H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-ASP-SER-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2;H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-ASP-SER-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH3;HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-ASP-SER-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2;HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-ASP-SER-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2 PORCINE;HSDGTFTSELSRLRDSARLQRLLQGLV-NH2;H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 hydrochloride salt CAS: 17034-35-4 MF: C130H220N44O41 MW: 3055.41 EINECS: 241-105-3 Product Categories: Peptide;Peptides for Cell Biology;Gastrointestinal Peptides;SecretinPeptides for Cell Biology;Hormones;Other Protein/Peptide Hormones;Secretins;Amino Acid Derivatives Mol File: 17034-35-4.mol Secretin Chemical Properties density  1.50±0.1 g/cm3(Predicted) storage temp.  2-8°C solubility  H2O:… ادامه خواندن Secretin

Olaparib Basic information Therapeutic agent of ovarian cancer Pharmacological effects Pharmacokinetics Drug Interactions Side effects Product Name: Olaparib Synonyms: 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]piperazin;Olaparid AZD2281;4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]Methyl]-1(2H)-phthalazinone;KU 59436;AZD2281(olaparib)/AZD-2281;AZD2281(olaparib);4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one;Olaparib-D8 CAS: 763113-22-0 MF: C24H23FN4O3 MW: 434.46 EINECS: 642-941-5 Product Categories: APIs;Inhibitors;Inhibitor;API;763113-22-0 Mol File: 763113-22-0.mol Olaparib Chemical Properties density  1.43 storage temp.  -20°C solubility  Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)… ادامه خواندن Olaparib

Rutaecarpine Basic information Product Name: Rutaecarpine Synonyms: :3,4]pyrido[2,1-b]quinazolin-5(7H)-one;Indolo(2′,3′:3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13-dihydro- (9CI);Rutecarpine (8CI);7,8-dihydroindolo[2′,3′:3,4]pyrido[2,1-b]quinazolin-5(13H)-one;RHETINE;8,13-DIHYDRO-INDOLO[2’3′:3,4]PYRIDO[2,1-B]QUINAZOLIN-5(7H)-ONE;RUTECARPINE 95+;Rutaecarpine std. CAS: 84-26-4 MF: C18H13N3O MW: 287.32 EINECS: 635-907-6 Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Indoles and derivatives;Inhibitors Mol File: 84-26-4.mol Rutaecarpine Chemical Properties Melting point  259.5-260° Boiling point  429.62°C (rough estimate) density  1.2030 (rough estimate) refractive… ادامه خواندن Rutaecarpine

1,1′-Carbonyldiimidazole Basic information Product Name: 1,1′-Carbonyldiimidazole Synonyms: LABOTEST-BB LT00233203;IM2 C O;(DIIMIDAZOL-1-YL)KETONE;AKOS BBS-00004316;RARECHEM AK HZ 0060;1,1′-CARBONYLBIS-1H-IMIDAZOLE;1.1′-CARBONYL-BIS-IMIDAZOLE;1,1′-CARBONYLDIIMIDAZOLE CAS: 530-62-1 MF: C7H6N4O MW: 162.15 EINECS: 208-488-9 Product Categories: Zero-Length Crosslinker;blocks;BuildingBlocks;pharma material;AMIDE;Peptide;Heterocycles;Intermediates;Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Peptide Coupling Reagents;Imidazoles;Biochemistry;Condensation & Active Esterification;Coupling Reactions (Peptide Synthesis);Peptide Synthesis;Synthetic Organic Chemistry;530-62-1 Mol File: 530-62-1.mol 1,1′-Carbonyldiimidazole Chemical Properties Melting point  117-122 °C(lit.) Boiling point  288.83°C (rough… ادامه خواندن 1,1′-Carbonyldiimidazole

Cephalomannine Basic information Product Name: Cephalomannine Synonyms: TAXOL B;BENZENEPROPANOICACID,ALPHA-HYDROXY-BETA-[(2-METHYL-1-OXO-2-BUTENYL)AMINO]-,6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA[3,4]BENZ[1,2-;BENZENEPROPANOIC ACID, ALPHA-HYDROXY-BETA-[(2-METHYL-1-OXO-2-BUTENYL)AMINO]-,6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA[3,4]BENZ[1,2-B]OXET-9-YL ESTER,[2AR-[2A,4,4A,6,9[R*,S*(E)],11,12,12A,12B]]-;CEPHALOMANNINE;paclitaxel iMpurity I;CephaloMannine, froM Taxus chinensis;(αR,βS)-α-Hydroxy-β-[[(2E)-2-Methyl-1-oxo-2-buten-1-yl]aMino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)- 12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester;NSC 318735 CAS: 71610-00-9 MF: C45H53NO14 MW: 831.9 EINECS: Product Categories: Inhibitors;Alkaloids;Antineoplastic and Immunosuppressive AntibioticsEnzyme Inhibitors by Enzyme;DNA polymerase – alphaAntibiotics;Antibiotics;Antibiotics A to;Antibiotics A-FAntibiotics;Antibiotics by Application;Chemical Structure Class;D to;Interferes with DNA SynthesisAntibiotics;Mechanism of Action;Penicillins and… ادامه خواندن Cephalomannine

Palonosetron Hydrochloride Basic information Nausea and vomiting drug Adverse effects References Product Name: Palonosetron Hydrochloride Synonyms: PALONOSETRON HYDROCHLORIDE;(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride;Onicit;RS-25259-197;(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one monohydrochloride;(S,S)-Palonosetron Hydrochloride;(S,S)-Palonosetron HCl;(3aS)-2-[(S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1-oxo-1H-benz[de]isoquinoline hydrochloride CAS: 135729-62-3 MF: C19H25ClN2O MW: 332.87 EINECS: 680-630-6 Product Categories: Selective 5-HT3 Receptor Antagonist;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;135729-62-3 Mol File: 135729-62-3.mol Palonosetron Hydrochloride Chemical Properties Melting point  >290°C alpha  D25 -94.1° (c = 0.4… ادامه خواندن Palonosetron Hydrochloride

Alantolactone Basic information Product Name: Alantolactone Synonyms: 8b-hydroxy-4ah-eudesm-5-en-12-oic acid;ALLANTOLACTONE;ALANTOLACTONE;[3ar-(3aa,5b,8ab,9aa)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho-[2,3-b]furan-2(3h)-one;[3aR-(3aalpha,5beta,8abeta,9aalpha)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one;Alantolactone (Helenin);helenin;4αH-Eudesma-5,11(13)-dien-12-oic acid, 8β-hydroxy-, γ-lactone (8CI) CAS: 546-43-0 MF: C15H20O2 MW: 232.32 EINECS: 208-899-3 Product Categories: Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Alkaloids;chiral Mol File: 546-43-0.mol Alantolactone Chemical Properties Melting point  78-79 C Boiling point  275 C alpha  D +175° (chloroform) density  1.0610… ادامه خواندن Alantolactone

NVP-BEZ 235 Basic information Product Name: NVP-BEZ 235 Synonyms: 4-[2,3-Dihydro-3-Methyl-2-oxo-8-(quinolin-3-yl)-1H-iMidazo[4,5-c]quinolin-1-yl]-alpha,alpha-diMethylbenzeneacetonitrile;BEZ-235;2-methyl-2-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl)propanenitrile;2-Methyl-2-[3-Methyl-2-oxo-8-(3-quinolinyl)-1-iMidazo[4,5-c]quinolinyl]propanenitrile;BEZ235 (NVP-BEZ235, Dactolisib);2-Methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl;BEZ235 NVP-BEZ235(BEZ235);Dactolisib CAS: 915019-65-7 MF: C30H23N5O MW: 469.55 EINECS: 1312995-182-4 Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;api;Inhibitors;Akt;mTOR;PI3K Mol File: 915019-65-7.mol NVP-BEZ 235 Chemical Properties Melting point  288-289°C Boiling point  701.0±70.0 °C(Predicted) density  1.299 storage temp.  Refrigerator solubility  Soluble in DMSO (up… ادامه خواندن NVP-BEZ 235

Olopatadine hydrochloride Basic information Product Name: Olopatadine hydrochloride Synonyms: OLOPATADINE HYDROCHLORIDE;OLOPATDINEHYDROCHLORIDE;OLOPATADINE HYDROCHLORIDE AND THE INTERMEDIATES;(Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride;Olopatadine Hydrochloride (150 mg);Olopatadin HCL (DFM Gr)INN;(11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride;AL-4943A CAS: 140462-76-6 MF: C21H24ClNO3 MW: 373.88 EINECS: 604-185-4 Product Categories: API;Opatanol, Pataday, Patanase, Allelock;APIs;Olopatadine;Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical material and intermeidates Mol File: 140462-76-6.mol Olopatadine hydrochloride Chemical Properties Melting point  242-245?C… ادامه خواندن Olopatadine hydrochloride

Venlafaxine hydrochloride Basic information Synthesis Product Name: Venlafaxine hydrochloride Synonyms: AKOS 92111;Effexor hydrochloride;Wy 45030 hydrochloride;(rs)-1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride;VENLAFAXINE HYDROCHLORIDE;1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)-cyclohexanohydrochloride;VENLAFAXINE HCI, 99%;VenlfaxineHydrochloride CAS: 99300-78-4 MF: C17H28ClNO2 MW: 313.86 EINECS: 619-421-1 Product Categories: Serotonin receptor;APIs;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Antidepressant;Active Pharmaceutical Ingredients;Medicine intermediate;99300-78-4 Mol File: 99300-78-4.mol Venlafaxine hydrochloride Chemical Properties Melting point  207-209°C Fp  9℃ storage temp.  2-8°C solubility  H2O: >10mg/mL… ادامه خواندن Venlafaxine hydrochloride