Ethyl 3-phenylpropionate

Ethyl 3-phenylpropionate Basic information
Product Name:Ethyl 3-phenylpropionate
Synonyms:ETHYL B-PHENYLPROPIONATE;ETHYL 3-PHENYLPROPIONATE;HYDROCINNAMIC ACID ETHYL ESTER;FEMA 2455;3- phenylethyl propionate;Ethyl hydrocinnaMate 99%;3-PHENYLPROPANOIC AID ETHYL ESTER;3-PHENYLPROPIONIC ACID ETHYL ESTER
CAS:2021-28-5
MF:C11H14O2
MW:178.23
EINECS:217-966-6
Product Categories:Aromatic Cinnamic Acids, Esters and Derivatives;Organic acids;Pharmaceutical Intermediates;2021-28-5
Mol File:2021-28-5.mol
Ethyl 3-phenylpropionate Structure
Ethyl 3-phenylpropionate Chemical Properties
Melting point 122-124 °C
Boiling point 247-248 °C(lit.)
density 1.01 g/mL at 25 °C(lit.)
refractive index n20/D 1.494(lit.)
FEMA 2455 | ETHYL 3-PHENYLPROPIONATE
Fp 226 °F
storage temp. 2-8°C
solubility Chloroform (Soluble), DMSO (Slightly), Methanol
form Oil
color Colourless
Specific Gravity1.013
Odorat 100.00 %. hyacinth rose honey fruity rum
Odor Typefloral
Water Solubility <0.1 g/100 mL at 25 ºC
JECFA Number644
BRN 1910432
InChIKeyJAGZUIGGHGTFHO-UHFFFAOYSA-N
LogP2.79
CAS DataBase Reference2021-28-5(CAS DataBase Reference)
NIST Chemistry ReferenceBenzenepropanoic acid, ethyl ester(2021-28-5)
EPA Substance Registry SystemEthyl 3-phenylpropionate (2021-28-5)
Safety Information
Safety Statements 23-24/25
WGK Germany 3
TSCA Yes
HS Code 29163900
MSDS Information
ProviderLanguage
3-Phenylpropionic acid ethyl esterEnglish
SigmaAldrichEnglish
ACROSEnglish
ALFAEnglish
Ethyl 3-phenylpropionate Usage And Synthesis
Chemical Propertiesclear colorless to light yellow liquid
Chemical PropertiesEthyl 3-phenylpropionate has an ethereal, rum, fruity, floral odor.
OccurrenceReported found in rum, passion fruit, plum brandy, caja fruit (Spondias lutea L.) and checkur (Alpinia sessilis).
UsesEthyl 3-phenylpropionate is used as an active pharmaceutical ingredient intermediate. It is also used in the synthesis of pyrimidine based inhibitors of cyclin-dependant kinases.
PreparationBy hydrogenation of the corresponding ethyl cinnamate in the presence of nickel in alcohol solution.
DefinitionChEBI: Ethyl 3-phenylpropanoate is a fatty acid ester.
Aroma threshold valuesDetection: 17 to 40 ppb
Synthesis Reference(s)The Journal of Organic Chemistry, 50, p. 3406, 1985 DOI: 10.1021/jo00218a033
Synthetic Communications, 22, p. 2683, 1992 DOI: 10.1080/00397919208021668
Tetrahedron Letters, 42, p. 781, 2001 DOI: 10.1016/S0040-4039(00)02176-6
General DescriptionClear colorless liquid.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileEthyl 3-phenylpropionate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Fire HazardThe flash point of Ethyl 3-phenylpropionate has not been determined. but Ethyl 3-phenylpropionate is probably combustible.
Ethyl 3-phenylpropionate Preparation Products And Raw materials
Raw materialsEthyl cinnamate–>ETHYL 2-PHENYLPROPIONATE–>Ethanol–>1,2-Ethanediyl, 1-phenyl- (9CI)
Preparation ProductsETHYL CYCLOHEXANEPROPIONATE–>2-(2-phenylethyl)chromone–>5-Benzyl-2,6-dichloronicotinonitrile

دیدگاهی بنویسید

نشانی ایمیل شما منتشر نخواهد شد. بخش‌های موردنیاز علامت‌گذاری شده‌اند *

ترجمه علمی مطالب این صفحه

شما می توانید مطالب این صفحه را به فارسی ترجمه کنید

تبادل مواد اولیه

آموزش

مجله مهندسی مواد

دسته بندی های مواد در یک نگاه