| 2-Chlorobenzothiazole Basic information |
| Product Name: | 2-Chlorobenzothiazole |
| Synonyms: | 2-CHLOROBENZOTHIAZOLE;2-BENZOTHIAZOLYL CHLORIDE;2-CHLORO-1,3-BENZOTHIAZOLE;2-Chlorobenzophiazole;2-chloro-benzothiazol;USAF ek-2784;usafek-2784;Benzothiazole, 2-chloro- (6CI,7CI,8CI,9CI) |
| CAS: | 615-20-3 |
| MF: | C7H4ClNS |
| MW: | 169.63 |
| EINECS: | 210-415-0 |
| Product Categories: | BENZOTHIAZOLE;API Intermediate;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Thiazoles;ThiazolesHeterocyclic Building Blocks |
| Mol File: | 615-20-3.mol |
 |
| 2-Chlorobenzothiazole Chemical Properties |
| Melting point | 21-23 °C (lit.) |
| Boiling point | 141 °C/30 mmHg (lit.) |
| density | 1.303 g/mL at 25 °C (lit.) |
| refractive index | n20/D 1.637(lit.) |
| Fp | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | -0.23±0.10(Predicted) |
| form | Liquid |
| Specific Gravity | 1.3711.303 |
| color | Clear yellow to yellow-brownish |
| Water Solubility | insoluble |
| BRN | 116316 |
| CAS DataBase Reference | 615-20-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzothiazole, 2-chloro-(615-20-3) |
| EPA Substance Registry System | 2-Chlorobenzothiazole (615-20-3) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 36/37/38-22-20/21/22 |
| Safety Statements | 23-24/25-37/39-26-36 |
| RIDADR | 2810 |
| WGK Germany | 3 |
| RTECS | DL3150000 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29342080 |
| Provider | Language |
|---|---|
| 2-Chloro-1,3-benzothiazole | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 2-Chlorobenzothiazole Usage And Synthesis |
| Chemical Properties | CLEAR YELLOW TO YELLOW-BROWNISH LIQUID |
| Uses | 2-Chlorobenzothiazole was used in the synthesis of: (RS)- and (S)-lubeluzole(1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone derivatives4H-thieno[2′,3′:4,5]pyrimido[2,1-b]benzothiazole derivatives |
| Uses | 2-Chloro-1,3-benzothiazole is used in the synthesis of CBTs which are good building blocks for bioluminescent compounds for imaging. |
| Purification Methods | It is purified by fractional distillation in vacuo. The 2-chloro-3-methylbenzothiazolinium 2,4-dinitrobenzenesulfonate crystallises from Ac2O, m 162-163o(dec). [Young & Amstutz J Am Chem Soc 73 4773 1951, Brower et al. J Org Chem 19 1830 1954, Hunter & Jones J Chem Soc 2190 1930, Beilstein 27 H 44, 27 II 18, 27 III/IV 1072.] |
| 2-Chlorobenzothiazole Preparation Products And Raw materials |