| 1,2,3,4-Tetrahydro-1-naphthol Basic information |
| Product Name: | 1,2,3,4-Tetrahydro-1-naphthol |
| Synonyms: | 1,2,3,4-tetrahydro-1-naphthaleno;1,2,3,4-Tetrahydro-1-naphthalenol;1,2,3,4-tetrahydro-1-naphtho;1,2,3,4-tetrahydro-1-napthol;1,2,3,4-Tetrahydro-alpha-naphthol;(S)-Tetralin-1-ol;(S)-Tetralin-1β-ol;1-Tetralinol |
| CAS: | 529-33-9 |
| MF: | C10H12O |
| MW: | 148.2 |
| EINECS: | 208-459-0 |
| Product Categories: | Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols |
| Mol File: | 529-33-9.mol |
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| 1,2,3,4-Tetrahydro-1-naphthol Chemical Properties |
| Melting point | 28-32 °C |
| Boiling point | 102-104 °C2 mm Hg(lit.) |
| density | 1.09 g/mL at 25 °C(lit.) |
| refractive index | n20/D 1.564(lit.) |
| Fp | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 5.09g/l |
| pka | 14.33±0.20(Predicted) |
| form | powder to lump to clear liquid |
| color | White or Colorless to Light yellow |
| Specific Gravity | 1.090 |
| BRN | 2046227 |
| LogP | 1.980 |
| CAS DataBase Reference | 529-33-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Naphthalenol, 1,2,3,4-tetrahydro-(529-33-9) |
| EPA Substance Registry System | 1-Naphthalenol, 1,2,3,4-tetrahydro- (529-33-9) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 22-24/25-37/39-26 |
| WGK Germany | 3 |
| RTECS | QL5075000 |
| HS Code | 29062900 |
| Provider | Language |
|---|---|
| alpha-Tetralol | English |
| SigmaAldrich | English |
| ACROS | English |
| 1,2,3,4-Tetrahydro-1-naphthol Usage And Synthesis |
| Chemical Properties | clear colourless to slightly brown viscous liquid |
| Uses | 1,2,3,4-Tetrahydro-1-naphthol was used as chiral probe to examine the role of three aromatic residues in enzyme-substrate interactions at the sulfuryl acceptor binding site of aryl sulfotransferase IV enzyme. |
| Synthesis Reference(s) | The Journal of Organic Chemistry, 61, p. 1493, 1996 DOI: 10.1021/jo951219c |
| General Description | (R)-(-)-enantiomer of 1,2,3,4-Tetrahydro-1-naphthol is a substrate for aryl sulfotransferase (AST) IV enzyme and (S)-(+)-1,2,3,4-tetrahydro-1-naphthol is a competitive inhibitor of AST IV-catalyzed sulfation of 1-naphthalenemethanol. It is the major urinary metabolite of tetralin. |
| 1,2,3,4-Tetrahydro-1-naphthol Preparation Products And Raw materials |
