| Scopine Basic information |
| Product Name: | Scopine |
| Synonyms: | SCOPINE;(1alpha,2beta,4beta,5alpha,7beta)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02.4]nonan-7-ol;SCOPINE, 97+%;(1α,2β,4β,5α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7β-ol;(1β,2α,4α,5β,7α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol;(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol;3-Oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol,9-Methyl-, (1a,2b,4b,5a,7b)-;Atropine Impurity 2 |
| CAS: | 498-45-3 |
| MF: | C8H13NO2 |
| MW: | 155.2 |
| EINECS: | 102-503-4 |
| Product Categories: | API intermediates;Tiotropium Bromide Intermediates;Inhibitors;498-45-3 |
| Mol File: | 498-45-3.mol |
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| Scopine Chemical Properties |
| Melting point | 73.0 to 77.0 °C |
| Boiling point | 281.3±40.0 °C(Predicted) |
| density | 1.284±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Dichloromethane; Methanol |
| pka | 14?+-.0.20(Predicted) |
| form | Solid |
| color | White |
| InChIKey | FIMXSEMBHGTNKT-RZVDLVGDSA-N |
| CAS DataBase Reference | 498-45-3(CAS DataBase Reference) |
| Safety Information |
| HS Code | 29349990 |
| Scopine Usage And Synthesis |
| Chemical Properties | White to white crystal powder |
| Uses | Scopin is an Intermediate in the synthesis of Scopine Methobromide (Tiotropium EP Impurity G) (S199985), an impurity of Tiotropium (T444850), an muscarinic receptor antagonist and bronchodilator. |
| Biological Activity | scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock. |
| Scopine Preparation Products And Raw materials |
| Raw materials | Scopolamine hydrobromide |