| Roxatidine acetate hydrochloride Basic information |
| Product Name: | Roxatidine acetate hydrochloride |
| Synonyms: | ROXATIDINE HCL ACETATE;2-(acetyloxy)-n-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-acetamidmonoh;2-acetoxy-n-(3-(m-(1-piperidinylmethyl)phenoxy)propyl)acetamidehydrochloride;2-hydroxy-n-(3-(m-(piperidinomethyl)phenoxy)propyl)-acetamidacetate(ester;2-hydroxy-n-(3-(m-(piperidinomethyl)phenoxy)propyl)acetamideacetate(ester);aceroxatidinehydrochloride;acetamide,2-hydroxy-n-(3-(m-(1-piperidinylmethyl)phenoxy)propyl)-,acetate,;tzu0460 |
| CAS: | 93793-83-0 |
| MF: | C19H29ClN2O4 |
| MW: | 384.89756 |
| EINECS: | 685-494-1 |
| Product Categories: | Miscellaneous Biochemicals;MEFOXIN;Other APIs;Amines;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API;93793-83-0 |
| Mol File: | 93793-83-0.mol |
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| Roxatidine acetate hydrochloride Chemical Properties |
| Melting point | 145-146° |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO: 78 mg/ml; Ethanol: 12 mg/ml; Water: 77 mg/ml |
| form | powder to crystal |
| color | White to Almost white |
| Merck | 14,8274 |
| Safety Information |
| RTECS | AC3855000 |
| Roxatidine acetate hydrochloride Usage And Synthesis |
| Description | Roxatidine acetate hydrochloride is an H2 antagonist, differing considerably in structure from other marketed agents(cimetidine, ranitidine and famotidine) in this category. It is useful in the treatment of gastric, duodenal and anastomotic ulcers, Zollinger-Ellison syndrome and peptic esophagitis. |
| Description | Roxatidine acetate is a competitive histamine H2 receptor antagonist that upon oral absorption is rapidly converted to its active metabolite roxatidine. By inhibiting the binding of histamine to H2 receptors, roxatidine reduces both intracellular cAMP concentrations and gastric acid secretion by parietal cells. |
| Chemical Properties | White Solid |
| Originator | Teikoku Hormone (Japan) |
| Uses | antibacterial |
| Uses | A histamine H2-receptor antagonist. It is used to inhibit gastric acid secretion; an antiulcer agent. |
| Definition | ChEBI: Roxatidine acetate hydrochloride is a member of piperidines. It contains a Roxane. |
| Brand name | ALTAT |
| Roxatidine acetate hydrochloride Preparation Products And Raw materials |