2-Bromo-6-nitrophenol

2-Bromo-6-nitrophenol Basic information
Product Name:2-Bromo-6-nitrophenol
Synonyms:TIMTEC-BB SBB008567;2-Bromo-6-nitropheno;3-Bromo-2-hydroxynitrobenzene;2-BROMO-6-NITROPHENOL;6-NITRO-2-BROMOPHENOL;Phenol, 2-broMo-6-nitro-;6-BroMo-2-nitrophenol;2-BroMo-6-nitrophenol, 97+%
CAS:13073-25-1
MF:C6H4BrNO3
MW:218
EINECS:629-309-4
Product Categories:Oxygen Compounds;Phenols;Fluorobenzene;Aromatic Phenols;Phenol&Thiophenol&Mercaptan;Organic Building Blocks
Mol File:13073-25-1.mol
2-Bromo-6-nitrophenol Structure
2-Bromo-6-nitrophenol Chemical Properties
Melting point 66-70 °C (lit.)
Boiling point 227.2±20.0 °C(Predicted)
density 1.881±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform; Methanol
form Solid
pka5.36±0.24(Predicted)
color Yellow
CAS DataBase Reference13073-25-1(CAS DataBase Reference)
EPA Substance Registry System2-Bromo-6-nitrophenol (13073-25-1)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 36/37-26
WGK Germany 3
Hazard Note Harmful
HazardClass IRRITANT
HS Code 29089990
MSDS Information
ProviderLanguage
SigmaAldrichEnglish
2-Bromo-6-nitrophenol Usage And Synthesis
Chemical PropertiesWhite solid
Uses2-Bromo-6-nitrophenol is an intermediate used in the synthesis of N-Hydroxy Eltrombopag (H825795), which is a derivative compound of Eltrombopag (508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
2-Bromo-6-nitrophenol Preparation Products And Raw materials
Raw materials1-Bromo-2-nitrobenzene–>3-Bromo-2-nitrophenol–>3-Bromo-4-nitrophenol–>1-Bromo-2-methoxy-3-nitro-benzene–>2-Bromo-4-nitrophenol–>Piperidine–>2-Nitrophenol
Preparation Products3”-AMINO-2”-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID–>2,4-DIBROMO-6-NITROPHENOL–>2-Bromo-3-nitrophenol–>4-Bromo-2-nitrophenol

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