2,6-Difluorobenzyl bromide

2,6-Difluorobenzyl bromide Basic information
Product Name:2,6-Difluorobenzyl bromide
Synonyms:2-BROMOMETHYL-1,3-DIFLUORO-BENZENE;2,6-DIFLUOROBENZYL BROMIDE;TIMTEC-BB SBB006564;ALPHA-BROMO-2,6-DIFLUOROTOLUENE;à-bromo-2,6-difluorotoluene;α-bromo-2,6-difluorotoluene;2,6-Difluorobenzyl bromide 98%;2,6-Difluorobenzylbromide98%
CAS:85118-00-9
MF:C7H5BrF2
MW:207.02
EINECS:285-652-6
Product Categories:Aromatic Halides (substituted);Miscellaneous;Fluoro-contained benzyl bromide series
Mol File:85118-00-9.mol
2,6-Difluorobenzyl bromide Structure
2,6-Difluorobenzyl bromide Chemical Properties
Melting point 52-55 °C(lit.)
Boiling point 184.9±25.0 °C(Predicted)
density 1,6 g/cm3
refractive index 1.5256 (estimate)
Fp >230 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Methanol[soluble in]
solubility soluble in Methanol
form Crystalline Powder
color Almost white to light beige
Sensitive Lachrymatory
BRN 2083943
InChIKeyLSXJPJGBWSZHTM-UHFFFAOYSA-N
CAS DataBase Reference85118-00-9(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 34-36
Safety Statements 26-36/37/39-45-25-27
RIDADR UN 3261 8/PG 2
WGK Germany 3
10-19-21
Hazard Note Corrosive/Lachrymatory
HazardClass 8
PackingGroup III
HS Code 29039990
MSDS Information
ProviderLanguage
ACROSEnglish
SigmaAldrichEnglish
ALFAEnglish
2,6-Difluorobenzyl bromide Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses2,6-Difluorobenzyl bromide has been used:
as reagent in alkylation of the quinazoline-2-thioxo-4-onein the synthesis of 1,3,5-triazine-2,4,6-trionesin the preparation of new classes of inhibitors of bovine viral diarrhea virus (as a surrogate virus for hepatitis C virus)
2,6-Difluorobenzyl bromide Preparation Products And Raw materials
Raw materials2,6-Difluorobenzyl alcohol–>2,6-Difluorotoluene–>Benzoic acid, 3,5-dichloro-2,4,6-trifluoro-, methyl ester–>2,6-Difluorobenzaldehyde–>METHYL 2,6-DIFLUOROBENZOATE
Preparation ProductsThieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 1-[(2,6-difluorophenyl)methyl]-5-methyl-6-(4-nitrophenyl)-3-phenyl-–>ethyl 2-((2,6-difluorobenzyl)(ethoxycarbonyl)amino)-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate

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