1-Bromo-2-chloroethane

1-Bromo-2-chloroethane Basic information
Product Name:1-Bromo-2-chloroethane
Synonyms:1-Brom-2-chlorethan;1-bromo-2-chloro-ethan;1-chloro-bromoethane(cbe);2-Bromo-1-chloroethane;1-Bromo-2-chloroethane, 98+%;ethylenbromchlorid;ai3-52297;beta-Chloroethyl bromide
CAS:107-04-0
MF:C2H4BrCl
MW:143.41
EINECS:203-456-0
Product Categories:omega-Haloalkyl Chlorides;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Alkyl;Building Blocks;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks;API Intermediate
Mol File:107-04-0.mol
1-Bromo-2-chloroethane Structure
1-Bromo-2-chloroethane Chemical Properties
Melting point −18-−14 °C(lit.)
Boiling point 106-107 °C(lit.)
density 1.723 g/mL at 25 °C(lit.)
refractive index n20/D 1.4884(lit.)
Fp 104-107°C
storage temp. Store below +30°C.
solubility water: soluble
form Liquid
color Clear colorless to slightly yellow
Water Solubility 7 g/L (20 ºC)
Sensitive Light Sensitive
BRN 605265
CAS DataBase Reference107-04-0(CAS DataBase Reference)
NIST Chemistry ReferenceEthane, 1-bromo-2-chloro-(107-04-0)
EPA Substance Registry System1-Bromo-2-chloroethane (107-04-0)
Safety Information
Hazard Codes T
Risk Statements 45-20/21-25-37/38-68-36/37/38-23/25
Safety Statements 53-36/37-45-38-36/37/39-28A
RIDADR UN 2810 6.1/PG 2
WGK Germany 3
RTECS KH6500000
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29034980
Hazardous Substances Data107-04-0(Hazardous Substances Data)
Toxicityrat,LD50,oral,64mg/kg (64mg/kg),”Pesticide Index,” Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 4, Pg. 73, 1969.
MSDS Information
ProviderLanguage
Ethylene chlorobromideEnglish
SigmaAldrichEnglish
ACROSEnglish
ALFAEnglish
1-Bromo-2-chloroethane Usage And Synthesis
Chemical PropertiesClear colorless to slightly yellow liquid
Uses1-Bromo-2-chloroethane was used in regio- and diastereoselective synthesis of 2-alkylidenetetrahydrofurans. 1-Bromo-2-chloroethane is used as a solvent and as an intermediate for organic synthesis. It is used as a as fumigant.
Uses1-Bromo-2-chloroethane was used in regio- and diastereoselective synthesis of 2-alkylidenetetrahydrofurans.
DefinitionChEBI: A bromoalkane that is bromoethane substituted by a chloro group at position 2.
General DescriptionClear colorless liquid with a sweet chloroform-like odor.
Air & Water ReactionsSlightly water soluble.
Reactivity Profile1-Bromo-2-chloroethane is incompatible with strong bases, strong oxidizing agents and magnesium .
Fire HazardLiterature sources indicate that 1-Bromo-2-chloroethane is nonflammable.
Purification MethodsWash it with conc H2SO4, water, 10% Na2CO3 solution, and again with water, then dry with CaCl2 and fractionally distil before use. [Beilstein 1 H 89, 1 I 28, 1 II 61, 1 III 179, 1 IV 155.]
1-Bromo-2-chloroethane Preparation Products And Raw materials
Raw materialsSodium carbonate–>2-Chloroethanol–>1-CHLORO-2-IODOETHANE–>2,2′-Dibromodiethyl ether
Preparation Products1-(2-CHLOROETHYL)NAPHTHALENE–>1,2-DIFLUOROETHANE–>4-(2-Chloroethyl)morpholine–>1-(2-Chloroethoxy)-4-nitrobenzene–>2-CHLOROETHYL PHENYL SULFIDE–>ETHYL 1-CYANOCYCLOPROPANECARBOXYLATE–>1-(5-broMopyridin-3-yl)cyclopropanecarbonitrile–>1-(3-METHOXYPHENYL)CYCLOPROPANECARBONITRILE–>2-[Tris(hydroxymethyl)methylamino]-1-ethanesulfonic acid–>1-(2-CHLOROETHOXY)-4-FLUOROBENZENE(WXC08215)

دیدگاهی بنویسید

نشانی ایمیل شما منتشر نخواهد شد. بخش‌های موردنیاز علامت‌گذاری شده‌اند *