| Thiophene-3-ethanol Basic information |
| Product Name: | Thiophene-3-ethanol |
| Synonyms: | 2-(3-Thienyl)ethanol, 3-(2-Hydroxyethy;3-(2-Hydroxyethyl)thiophene 98%;2-(thiophen-3-yl)ethanol;2-(3-Thienyl)ethanol, 3-(2-Hydroxyethyl)thiophene;2-(Thiophene-3-yl)ethanol;2-(3-Thienyl)ethanol,99%;2-(3-Thienyl)ethanol ,98%;2-(Thien-3-yl)ethan-1-ol |
| CAS: | 13781-67-4 |
| MF: | C6H8OS |
| MW: | 128.19 |
| EINECS: | 237-434-7 |
| Product Categories: | Thiophen;Functional Materials;Heterocycles;Thiophens;Reagents for Conducting Polymer Research;Thiophene Derivatives (for Conduting Polymer Research);1 |
| Mol File: | 13781-67-4.mol |
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| Thiophene-3-ethanol Chemical Properties |
| Boiling point | 110-111 °C14 mm Hg(lit.) |
| density | 1.144 g/mL at 25 °C(lit.) |
| refractive index | n20/D 1.552(lit.) |
| Fp | 199 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 14.92±0.10(Predicted) |
| form | Liquid |
| color | Clear colorless to yellow-brown |
| Specific Gravity | 1.144 |
| Water Solubility | Sparingly soluble in water(0.059 g/L at 25°C). |
| BRN | 107080 |
| InChIKey | YYPNNBPPDFTQFX-UHFFFAOYSA-N |
| LogP | 1.07 |
| CAS DataBase Reference | 13781-67-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Thiopheneethanol(13781-67-4) |
| Safety Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| Thiophene-3-ethanol Usage And Synthesis |
| Chemical Properties | Clear colorless to yellowish-brown liquid |
| Uses | 3-Thiopheneethanol is used as a reagent in the synthesis of pH-responsive near-IR emitting conjugated polymer nanoparticles for cellular imaging and controlled-drug delivery. 3-Thiopheneethanol is also used as a reagent in the preparation of potent respiratory syncytial virus RNA polymerase inhibitors. |
| Uses | 3-Thiopheneethanol [3-(2-hydroxyethyl)thiophene] was used in the synthesis of various ether and ester derivatives such as 3-(2-(benzyloxy)ethyl)thiophene, 3-[2-((triphenylmethyl)oxy)ethyl]thiophene, 3-[2-((trimethylsilyl)oxy)ethyl]thiophene, 3-[2-((dimethyl-tert-butylsilyl)oxy)ethyl]thiophene, 3-(2-acetoxyethyl)thiophene and 3-(2-(benzoyloxy)ethyl)thiophene. |
| Thiophene-3-ethanol Preparation Products And Raw materials |
| Raw materials | Tetrahydrofuran–>n-Butyllithium–>Lithium Aluminum Hydride–>Nitrogen–>Methyl chloroacetate–>3-Bromothiophene |
| Preparation Products | 2-(thiophen-3-yl)ethyl 4-methylbenzenesulfonate |