Methyl 2-aminopyridine-4-carboxylate

Methyl 2-aminopyridine-4-carboxylate Basic information
Product Name:Methyl 2-aminopyridine-4-carboxylate
Synonyms:METHYL 2-AMINOISONICOTINATE;METHYL 2-AMINOPYRIDINE-4-CARBOXYLATE;CHEMBRDG-BB 4015127;2-Aminopyridinecarboxylic acid methyl ester~Methyl 2-aminoisonicotinate;2-Aminopyridine-4-carboxylic acid methyl ester;2-aminopyridinecarboxylic acid methyl ester;2-amino-3-methyl-4-pyridinecarboxylate;Methyl 2-aminoisonicotinate 98%
CAS:6937-03-7
MF:C7H8N2O2
MW:152.15
EINECS:627-546-8
Product Categories:Amines;Heterocycles;Esters;Pyridines;Pyridine;Inhibitors;API intermediates;Heterocycle-Pyridine series
Mol File:6937-03-7.mol
Methyl 2-aminopyridine-4-carboxylate Structure
Methyl 2-aminopyridine-4-carboxylate Chemical Properties
Melting point 144-148 °C
Boiling point 296.1±20.0 °C(Predicted)
density 1.238±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform
pka4.89±0.11(Predicted)
form Crystalline Powder
color White to brown
Water Solubility Insoluble in water.
BRN 128642
CAS DataBase Reference6937-03-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-41-20/22
Safety Statements 26-36-26/36-39-36/37/39-22
HazardClass IRRITANT
HS Code 29333990
MSDS Information
ProviderLanguage
ALFAEnglish
Methyl 2-aminopyridine-4-carboxylate Usage And Synthesis
Chemical PropertiesTan Solid
UsesA nitrogen monoxide synthetase inhibitor.
UsesMethyl 2-aminopyridine-4-carboxylate is an inhibitor of nitrogen monoxide synthetase.
Synthesis Reference(s)The Journal of Organic Chemistry, 72, p. 4554, 2007 DOI: 10.1021/jo070189y
Methyl 2-aminopyridine-4-carboxylate Preparation Products And Raw materials
Preparation ProductsTERT-BUTYL 4-(AMINOMETHYL)PYRIDIN-2-YLCARBAMATE–>(2-TERT-BUTOXYFORMAMIDO-PYRIDIN-4-YL)METHYL METHANESULFONATE–>TERT-BUTYL 4-(HYDROXYMETHYL)PYRIDIN-2-YLCARBAMATE–>TERT-BUTYL 4-(METHOXYCARBONYL)PYRIDIN-2-YLCARBAMATE–>Methyl 2-aMino-5-chloropyridine-4-carboxylate–>2-(2-Amino-4-pyridyl)-2-propanol

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