7-Fluoro-6-nitro-4-hydroxyquinazoline Basic information |
Product Name: | 7-Fluoro-6-nitro-4-hydroxyquinazoline |
Synonyms: | 7-FLUORO-6-NITRO-4-HYDROXY-QUINAZOLINE;7-FLUORO-6-NITRO QUINAZOLINONE;7-Fluoro-6-Nitro-4(H)-Quinazoline;6-Nitro-7-Fluoro-4-HydroxyQuinazoline;7-fluoro-6-nitroquinazolin-4(1H)-one;7-Fluoro-6-nitro-1H-quina…;4(1H)-QUINAZOLINONE, 7-FLUORO-6-NITRO-;7-fluoro-6-nitroquinazolin-4-ol |
CAS: | 162012-69-3 |
MF: | C8H4FN3O3 |
MW: | 209.13 |
EINECS: | 1308068-626-2 |
Product Categories: | Intermediate |
Mol File: | 162012-69-3.mol |
7-Fluoro-6-nitro-4-hydroxyquinazoline Chemical Properties |
Melting point | 282-285 °C(Solv: acetic acid (64-19-7)) |
Boiling point | 407.6±55.0 °C(Predicted) |
density | 1.75±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | powder to crystal |
pka | -2.69±0.20(Predicted) |
color | Light yellow to Yellow to Orange |
CAS DataBase Reference | 162012-69-3(CAS DataBase Reference) |
Safety Information |
7-Fluoro-6-nitro-4-hydroxyquinazoline Usage And Synthesis |
Uses | 7-Fluoro-6-nitroquinazolin-4(3H)-one, is an intermediate in the preparation of kinase inhibitors, such as ATP Site inhibitors of the Tyrosine Kinase activity of the epidermal growth factor receptor. |
7-Fluoro-6-nitro-4-hydroxyquinazoline Preparation Products And Raw materials |
Preparation Products | N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine |