6,7-Dimethoxyquinazoline-2,4-dione

6,7-Dimethoxyquinazoline-2,4-dione Basic information
Product Name:6,7-Dimethoxyquinazoline-2,4-dione
Synonyms:QUINAZOLINDIONE;2,4-Dihydroxy-6,7-dimethoxquinazoline;2,4-DIONE-6,7-DIMETHOXYQUINAZOLINE;2,4-DIHYDROXY-6,7-DIMETHOXYQUINAZOLINE;LABOTEST-BB LT00453115;1,2,3,4-TETRAHYDRO-6,7-DIMETHOXYQUINAZOLINE-2,4-DIONE;6,7-DIMETHOXY-(1H,3H)-2,4-QUINAZOLINDIONE;6,7-DIMETHOXY-2,4(1H,3H)-QUINAZOLINEDIONE
CAS:28888-44-0
MF:C10H10N2O4
MW:222.2
EINECS:249-288-1
Product Categories:Aromatics;Heterocycles;Building Blocks;Heterocyclic Building Blocks;Intermediates & Fine Chemicals;Pharmaceuticals;Quinolines, Quinazolines and derivatives;Quinoline&Isoquinoline;Doxazosin;Quinazolines
Mol File:28888-44-0.mol
6,7-Dimethoxyquinazoline-2,4-dione Structure
6,7-Dimethoxyquinazoline-2,4-dione Chemical Properties
Melting point >300 °C (lit.)
Boiling point 363.37°C (rough estimate)
density 1.3404 (rough estimate)
refractive index 1.6300 (estimate)
storage temp. 2-8°C
solubility Aqueous Acid (Sparingly)
form neat
pka10.27±0.20(Predicted)
color White to Off-White
Water Solubility insoluble
BRN 204597
CAS DataBase Reference28888-44-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
HS Code 29339990
MSDS Information
ProviderLanguage
6,7-Dimethoxyquinazoline-2,4-dioneEnglish
SigmaAldrichEnglish
ACROSEnglish
ALFAEnglish
6,7-Dimethoxyquinazoline-2,4-dione Usage And Synthesis
Chemical Propertiesbrown powder
UsesAn intermediate in the preparation of Alfuzosin hydrochloride (A532000), an antihypertensive.
Uses6,7-Dimethoxyquinazoline-2,4-dione (Doxazosin EP Impurity D) is an intermediate in the preparation of Alfuzosin hydrochloride (A532000), an antihypertensive.
6,7-Dimethoxyquinazoline-2,4-dione Preparation Products And Raw materials
Preparation Products2-Chloro-4-amino-6,7-dimethoxyquinazoline

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