6-Fluoronicotinic acid

6-Fluoronicotinic acid Basic information
Product Name:6-Fluoronicotinic acid
Synonyms:2-Fluoropyridine-5-carboxylic acid, 6-Fluoropyridine-3-carboxylic acid, 5-Carboxy-2-fluoropyridine, 3-Carboxy-6-fluoropyridine;6-Floronicotinic acid;6-Fluoronicotinc Acid;2-Fluoropyridine-5-carboxylic acid, 6-Fluoropyridine-3-carboxylic acid, 5-Carboxy-2-fluoropyridine;2-FLUOROPYRIDINE-5-CARBOXYLIC ACID;2-FLUORO-5-PYRIDINE CARBOXYLIC ACID;2-Fluoro-5-pyridine carboxylic acid(6-Fluoronicotinic acid);6-FLUORONICOTINIC ACID
CAS:403-45-2
MF:C6H4FNO2
MW:141.1
EINECS:
Product Categories:C6;Chemical Synthesis;Fluorinated Building Blocks;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles;Pyridine;Pyridine series;Pyridines;Building Blocks;Carboxy;Boronic Acid;Picolinic acid series;API
Mol File:403-45-2.mol
6-Fluoronicotinic acid Structure
6-Fluoronicotinic acid Chemical Properties
Melting point 144-148 °C(lit.)
Boiling point 309.4±22.0 °C(Predicted)
density 1.419±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form powder to crystal
pka3.41±0.10(Predicted)
color White to Orange to Green
CAS DataBase Reference403-45-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HazardClass IRRITANT
HS Code 29333990
MSDS Information
ProviderLanguage
SigmaAldrichEnglish
6-Fluoronicotinic acid Usage And Synthesis
Chemical PropertiesWhite solid
UsesIt is used as a pharmaceutical intermediate.
6-Fluoronicotinic acid Preparation Products And Raw materials
Raw materialsSodium nitrite–>Potassium permanganate–>Fluoroboric acid–>2-Amino-5-methylpyridine–>2-Fluoro-5-iodopyridine–>2-Fluoro-5-methylpyridine–>3-Pyridinecarbonyl chloride, 6-fluoro- (9CI)–>Nicotinic acid
Preparation Products2-Fluoro-5-bromopyridine

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