(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Basic information
Product Name:(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
Synonyms:(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-(Tert-butoxycarbonyl)-2-azabicyclo-[2.2.1]-heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%;2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 2-(1,1-diMethylethyl) ester, (1R,3S,4S)-;(1R,3S,4S)-3-[(2-methylpropoxy)carbonyl]-2-azabicyclo[2.2.1]heptane-2-carboxylic acid;Ledipasvir INT 2;Ledipasvir Impurity 14
CAS:291775-59-2
MF:C12H19NO4
MW:241.28
EINECS:808-164-2
Product Categories:Pharmaceuticalintermediates
Mol File:291775-59-2.mol
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Structure
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Chemical Properties
Melting point 147-152 °C
Boiling point 371.0±25.0 °C(Predicted)
density 1.232±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka4.05±0.20(Predicted)
optical activity[α]22/D -170±10°, c = 1 in chloroform
InChIKeyIFAMSTPTNRJBRG-YIZRAAEISA-N
Safety Information
Hazard Codes Xi,N
Risk Statements 61-36/37/38
Safety Statements 53-26-61
RIDADR UN 3077 9/PG 3
WGK Germany 3
MSDS Information
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Usage And Synthesis
Uses(1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-??daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants.
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Preparation Products And Raw materials

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