3-(4-Chlorbutyl)-1H-indol-5-carbonitril

3-(4-Chlorbutyl)-1H-indol-5-carbonitril Basic information
Product Name:3-(4-Chlorbutyl)-1H-indol-5-carbonitril
Synonyms:3-(4-Chlorobutyl)indole-5-carbonitrile;3-(4-Chlorbutyl)-1H-indol-5-carbonitril;Vilazodone Hydrochloride Intermediate;Chlorobutyl)indole-5-carbonitrile, 3-(4-;1H-Indole-5-carbonitrile, 3-(4-chlorobutyl)-;InterMediate of Vilazodone;3-(4-Chlorbutyl)-1H-indol-5-carbonitrile;3-(4-chloro-butyl)-5-cyanoindole
CAS:143612-79-7
MF:C13H13ClN2
MW:232.71
EINECS:801-938-0
Product Categories:Aromatics;Heterocycles;Intermediates;Inhibitors
Mol File:143612-79-7.mol
3-(4-Chlorbutyl)-1H-indol-5-carbonitril Structure
3-(4-Chlorbutyl)-1H-indol-5-carbonitril Chemical Properties
Melting point 99-100℃
Boiling point 448.1±35.0 °C(Predicted)
density 1.22
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly, Ethyl Acetate (Slightly)
form Solid
pka15.93±0.30(Predicted)
color Off-White to Pale Beige
CAS DataBase Reference143612-79-7
Safety Information
MSDS Information
3-(4-Chlorbutyl)-1H-indol-5-carbonitril Usage And Synthesis
UsesReactant in the preparation of allosteric IGF-1R inhibitors, and dual 5-HT1A receptor agonists and serotonin reuptake inhibitors.
3-(4-Chlorbutyl)-1H-indol-5-carbonitril Preparation Products And Raw materials
Raw materialsBenzonitrile, 4-[(2E)-2-(6-chlorohexylidene)hydrazinyl]-–>Hexane, 6-chloro-1,1-dimethoxy-–>6-CHLOROHEXANAL–>4-Cyanophenylhydrazine hydrochloride–>5-Cyanoindole–>3-(4-chlorobutyl)-1-tosyl-1H-indole-5-carbonitrile–>3-(4-chlorobutanoyl)-1H-indole-5-carbonitrile–>6-CHLOROHEXYLZINC BROMIDE–>Benzenediazonium, 4-cyano-, tetrafluoroborate(1-)–>Trimethoxymethane–>1-Bromo-4-chlorobutane–>N,N-Dimethylformamide dimethyl acetal
Preparation Products5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-Benzofurancarboxylic acid

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