| (S)-(+)-3-Hydroxytetrahydrofuran Basic information |
| Product Name: | (S)-(+)-3-Hydroxytetrahydrofuran |
| Synonyms: | (S)-TETRAHYDROFURAN-3-OL;(S)-(+)-TETRAHYDRO-3-FURANOL;(S)-(+)-3-HYDROXY TETAHYDRO FURAN;(S)-(-)-3-HYDROXY TETRAHYDRO FURAN;(3S)-oxolan-3-ol;(2S)-1,4-Epoxy-2-hydroxybutane, (3S)-Tetrahydrofuran-3-ol, (3S)-Oxolan-3-ol;Afatinib intermediate B;(S)-(+)-3-Hydroxytetrahydrofuran, ee: 95% |
| CAS: | 86087-23-2 |
| MF: | C4H8O2 |
| MW: | 88.11 |
| EINECS: | 425-090-2 |
| Product Categories: | Afatinib intermediate;Chiral Building Blocks;Chiral Reagents;Furans;Simple Alcohols (Chiral);Synthetic Organic Chemistry;Alcohols, Hydroxy Esters and Derivatives;Chiral Compounds;Starting Raw Materials & Intermediates;Small molecule;Tetrahydrofuran Series;bc0001 |
| Mol File: | 86087-23-2.mol |
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| (S)-(+)-3-Hydroxytetrahydrofuran Chemical Properties |
| Boiling point | 80 °C/15 mmHg (lit.) |
| alpha | 18.5 º (c=2 MeOH) |
| density | 1.103 g/mL at 25 °C (lit.) |
| vapor pressure | 47Pa at 25℃ |
| refractive index | n20/D 1.45(lit.) |
| Fp | 175 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol (Slightly) |
| pka | 14.49±0.20(Predicted) |
| form | Liquid |
| Specific Gravity | 1.11 |
| color | Clear colorless to pale yellow |
| optical activity | [α]20/D +17.5°, c = 2.4 in methanol |
| Water Solubility | soluble |
| BRN | 4652609 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | XDPCNPCKDGQBAN-BYPYZUCNSA-N |
| LogP | -0.784 at 22℃ and pH6.8 |
| Surface tension | 72mN/m at 1g/L and 25℃ |
| CAS DataBase Reference | 86087-23-2(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | 3 |
| HS Code | 29321900 |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ACROS | English |
| (S)-(+)-3-Hydroxytetrahydrofuran Usage And Synthesis |
| Chemical Properties | Colourless Liquid |
| Uses | Amprenavir and Fosamprenavir intermediate |
| Uses | (S)-(+)-3-Hydroxytetrahydrofuran is a useful reagent for the preparation of pyrazolo triazin ylamine derivatives as adenosine receptor antagonists. |
| (S)-(+)-3-Hydroxytetrahydrofuran Preparation Products And Raw materials |