6-Fluoroquinaldine Basic information |
Product Name: | 6-Fluoroquinaldine |
Synonyms: | 6-Fluoro-2-methylquinoline, 98+%;6-Fluoro-2-methyl-1-azanaphthalene;AKOS 1002;6-FLUORO-2-METHYLQUINOLINE;6-FLUOROQUINALDINE;6-Fluoro-2-methylquinoline 97%;6-Fluoro-2-methylquinoline97%;2-METHYL-6-FLUOROQUINOLINE |
CAS: | 1128-61-6 |
MF: | C10H8FN |
MW: | 161.18 |
EINECS: | 214-439-2 |
Product Categories: | Aromatics Compounds;Quinolines, Quinazolines and derivatives;Quinoline&Isoquinoline;Alkylquinolines;Haloquinolines;Quinolines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Building Blocks;Heterocyclic Building Blocks |
Mol File: | 1128-61-6.mol |
6-Fluoroquinaldine Chemical Properties |
Melting point | 49-53 °C (lit.) |
Boiling point | 99 °C / 3mmHg |
density | 1.1465 (estimate) |
Fp | >230 °F |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Soluble in Chloroform. |
pka | 5.16±0.43(Predicted) |
form | powder to crystal |
color | White to Almost white |
BRN | 1281677 |
CAS DataBase Reference | 1128-61-6(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 38-41-36/37/38 |
Safety Statements | 26-37/39-36 |
WGK Germany | 3 |
Hazard Note | Irritant |
HS Code | 29334990 |
Provider | Language |
---|---|
SigmaAldrich | English |
ACROS | English |
ALFA | English |
6-Fluoroquinaldine Usage And Synthesis |
Chemical Properties | brown powder or granules |
Uses | Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Br?nsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent. |
Uses | Quinoline derivative as a highly potent thrombin receptor antagonist |
6-Fluoroquinaldine Preparation Products And Raw materials |