| 7-Methylquinoline Basic information |
| Product Name: | 7-Methylquinoline |
| Synonyms: | m-Toluquinoline;7-methyl-quinolin;Quinolinol,7-methyl-;7-METHYLQUINOLINE;7-Methylquinolinol;7-Methylquinoline,tech.70%;7-Methylquinoline,97%;7-Methylquiuoline |
| CAS: | 612-60-2 |
| MF: | C10H9N |
| MW: | 143.19 |
| EINECS: | 210-316-2 |
| Product Categories: | Alkylquinolines;Quinolines;Quinoline&Isoquinoline;Quinoline Derivertives;Building Blocks;Heterocyclic Building Blocks |
| Mol File: | 612-60-2.mol |
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| 7-Methylquinoline Chemical Properties |
| Melting point | 35-37 °C(lit.) |
| Boiling point | 258 °C(lit.) |
| density | 1.061 |
| refractive index | 1.6070 to 1.6210 |
| Fp | >230 °F |
| storage temp. | Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 5.44±0.14(Predicted) |
| form | Viscous Liquid |
| color | Off-White to Pale Beige Low-Melting |
| Water Solubility | <0.1 g/100 mL at 20 ºC |
| BRN | 110317 |
| Stability: | Stable. Incompatible with strong oxidizing agents, strong acids. May be light sensitive. |
| InChIKey | KDYVCOSVYOSHOL-UHFFFAOYSA-N |
| CAS DataBase Reference | 612-60-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Quinoline, 7-methyl-(612-60-2) |
| EPA Substance Registry System | 7-Methylquinoline (612-60-2) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-39 |
| WGK Germany | 3 |
| RTECS | VC0560000 |
| TSCA | Yes |
| HS Code | 29334900 |
| Provider | Language |
|---|---|
| 7-Methylquinoline | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 7-Methylquinoline Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder |
| Uses | 7-methylquinoline has been bioassayed as tumor initiator on the skin of Sencar mice. |
| General Description | 7-Methylquinoline is a reagent used in the preparation of diarylmethylpiperazines as potent opioid receptor agonists with improved side effects. Also used in the preparation of novel pyrazine compounds derived from 2-phenylquinolin-7-yl which act as potent insulin-like growth factor-I receptor inhibitors. |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | 7-Methylquinoline may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. |
| Fire Hazard | 7-Methylquinoline is combustible. |
| Purification Methods | Purify it via its dichromate complex (m 149o, after five recrystallisations from water). [Cumper et al. J Chem Soc 1176 1962, Beilstein 20 III/IV 3497, 20/7 V 402.] |
| 7-Methylquinoline Preparation Products And Raw materials |