| 2′,5′-Dimethoxyacetophenone Basic information |
| Product Name: | 2′,5′-Dimethoxyacetophenone |
| Synonyms: | Methyl 2,5-dimethoxyphenyl ketone;2,5-Dimethoxy acetonphenone;2′,5′-Dimethoxyacetophenone,99%;2′,5′-Dimethoxyaceto;1-(2,5-dimethoxyphenyl)-ethanon;Acetophenone, 2′,5′-dimethoxy-;AKOS BBS-00004326;1-(2,5-dimethoxyphenyl)-ethanone |
| CAS: | 1201-38-3 |
| MF: | C10H12O3 |
| MW: | 180.2 |
| EINECS: | 214-858-0 |
| Product Categories: | Aromatic Acetophenones & Derivatives (substituted);C10;Carbonyl Compounds;Ketones;Acetophenone series;1201-38-3 |
| Mol File: | 1201-38-3.mol |
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| 2′,5′-Dimethoxyacetophenone Chemical Properties |
| Melting point | 18-20 °C(lit.) |
| Boiling point | 155-158 °C11 mm Hg(lit.) |
| density | 1.139 g/mL at 25 °C(lit.) |
| refractive index | n20/D 1.5441(lit.) |
| Fp | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Methanol (Slightly) |
| form | Liquid |
| color | Clear yellow to green-yellow |
| BRN | 2047423 |
| InChIKey | FAXUIYJKGGUCBO-UHFFFAOYSA-N |
| LogP | 2.125 (est) |
| CAS DataBase Reference | 1201-38-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanone, 1-(2,5-dimethoxyphenyl)-(1201-38-3) |
| EPA Substance Registry System | Ethanone, 1-(2,5-dimethoxyphenyl)- (1201-38-3) |
| Safety Information |
| Provider | Language |
|---|---|
| 2′,5′-Dimethoxyacetophenone | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 2′,5′-Dimethoxyacetophenone Usage And Synthesis |
| Chemical Properties | clear yellow to green-yellow liquid |
| Uses | 2”,5”-Dimethoxyacetophenone is a useful building block which has been used in the preparation of pyridine and thieno[2,3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors, and in the synthesis of anti-cancer and apoptosis-inducing agents. |
| Preparation | Obtained by reaction of dimethyl sulfate with quinacetophenone in the presence of 10% aqueous sodium hydroxide. |
| 2′,5′-Dimethoxyacetophenone Preparation Products And Raw materials |