| Tetrabutylammonium fluoride Basic information |
| Product Name: | Tetrabutylammonium fluoride |
| Synonyms: | TETRA BUTYL AMMONIUM FLUORIDE (1M SOLUTION IN THF);Tetra-n-butylammonium fluoride, 75% w/w aq. soln.;Tetrabutylammonium Fluoride (1mol/L in Tetrahydrofuran);Tetrabutylammonium fluoride on silica gel, 1 mmole TBAF/g reagent;Tetrabutylaminium·fluoride;TETRABUTYLAMMONIUM FLUORIDE, 1M SOLUTION IN THF, CONTAINING CA;TETRABUTYLAMMONIUM FLUORIDE, 1.0M IN THF;Tetrabutylammonium fluoride (ca. 1mol/L in Tetrahydrofuran) |
| CAS: | 429-41-4 |
| MF: | C16H36FN |
| MW: | 261.46 |
| EINECS: | 207-057-2 |
| Product Categories: | metal halide;quarternary ammonium salts;Reagents;Silica Gel;Supported Synthesis;Fluoride SourcesSupported Synthesis;Deprotecting Reagents;Others;Protection and Derivatization;Supported Reagents;Fluorinating Reagents;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Nucleophilic Fluorinating Reagents;Ammonium Fluorides (Quaternary);Fluorination;Halogenation;Quaternary Ammonium Compounds;Synthetic Organic Chemistry;bc0001 |
| Mol File: | 429-41-4.mol |
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| Tetrabutylammonium fluoride Chemical Properties |
| Melting point | 62-63 °C(lit.) |
| density | 0.953 g/mL at 25 °C |
| refractive index | n20/D 1.456 |
| Fp | 1 °F |
| storage temp. | 2-8°C |
| solubility | Miscible with terahydrofuran, acetonitrile, dimethyl sulfoxide and organic solvents. |
| form | Solution |
| color | Clear light greenish to brown |
| Water Solubility | Insoluble in water. |
| Sensitive | Hygroscopic |
| Merck | 14,9187 |
| BRN | 3570522 |
| Exposure limits | ACGIH: TWA 2.5 mg/m3 NIOSH: IDLH 250 mg/m3 |
| CAS DataBase Reference | 429-41-4(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Butanaminium, N,N,N-tributyl-, fluoride (429-41-4) |
| Safety Information |
| Hazard Codes | C,F,Xi |
| Risk Statements | 34-19-11-36/37/38-40-37 |
| Safety Statements | 26-27-36/37/39-45-33-29-16-36 |
| RIDADR | UN 3261 8/PG 2 |
| WGK Germany | 3 |
| F | 3 |
| Hazard Note | Flammable/Irritant |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29239000 |
| Provider | Language |
|---|---|
| TBAF | English |
| SigmaAldrich | English |
| Tetrabutylammonium fluoride Usage And Synthesis |
| Chemical Properties | Clear light greenish to amber or brown solution |
| Uses | Catalyst for etherification of alcohols and phenols with alkyl halides Catalyst for benzylation reactions. |
| Uses | Tetrabutylammonium fluoride is a reagent in organic syntheses in addition, condensation, base-catalyzed cyclization reactions, fluorination and desulfonylation reactions and as a deprotecting agent. Typically dried prior to use. |
| Uses | Tetrabutylammonium fluoride (TBAF) is a commonly used organic soluble fluoride salt. It is used as a base, a phase transfer catalyst, and as a fluoride source. In the research field of fluoride sensor development, TBAF is used as an easy to handle and measurable fluoride anion source. The fluoride in TBAF, once dissolved, can be thought of as a free fluoride with little interaction with the ammonium cation. Since TBAF should not absorb light at wavelengths greater than 240nm, it is useful to monitor sensing reactions with visible spectroscopy. |
| Definition | ChEBI: Tetrabutylammonium fluoride is a fluoride salt and a tetrabutylammonium salt. It has a role as a phase-transfer catalyst. |
| Tetrabutylammonium fluoride Preparation Products And Raw materials |