Tween 60

Tween 60 Basic information
Product Name:Tween 60
Synonyms:POLYSORBATE 60 USP/NF;POLYSORBATE 60 extrapure;Polysorbat 60;Polysorbatum 60, Tween(R) 60;Polyethylene glycol sorbitan monostearate, Polyoxyethylene sorbitan monostearate;TWEEN(R) 61;Lonzest(R) SMS-20;Glycos S-20 KFG
CAS:9005-67-8
MF:C64H126O26
MW:0
EINECS:500-020-4
Product Categories:Cosmetic Ingredients & Chemicals;Detergents;Detergents A to ZDetergents;Non-Ionic;Biochemistry;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);Ester Ether Type (Surfactants);Functional Materials;Nonionic Surfactants;Surfactants;9005-67-8
Mol File:Mol File
Tween 60 Structure
Tween 60 Chemical Properties
Melting point 45-50 °C
Boiling point 802.68°C (rough estimate)
density 1.044 g/mL at 25 °C(lit.)
vapor pressure <10 hPa (20 °C)
FEMA 2916 | POLYSORBATE 60
refractive index n20/D 1.474
Fp >230 °F
storage temp. Store below +30°C.
solubility 100 g/L
pka0[at 20 ℃]
form powder to lump to clear liquid
color White or Colorless to Yellow
Odormild alcoholic
PH5.5-7.7 (50g/l, H2O, 25℃)
Odor Typealcoholic
Water Solubility 100 g/L
FreezingPoint 21.0 to 25.0 ℃
Merck 14,7582
Hydrophilic-Lipophilic Balance (HLB)15
LogP3.938 at 25℃
EPA Substance Registry SystemPolysorbate 60 (9005-67-8)
Safety Information
Safety Statements 24/25
WGK Germany 1
RTECS WG2934000
TSCA Yes
HS Code 34021300
ToxicityLD50 orally in Rabbit: > 38000 mg/kg
MSDS Information
ProviderLanguage
Tween 60English
SigmaAldrichEnglish
ACROSEnglish
ALFAEnglish
Tween 60 Usage And Synthesis
Chemical PropertiesPolysorbate 60 has a faint, characteristic odor and a warm, somewhat bitter taste. It is a mixture of stearate and palmitate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides.
Chemical PropertiesTan paste
UsesGlycosperse(R) S-20 KFG is used as an emulsifier. Suggested applications: cakes, shortenings, milk substitute, chocolate flavored syrup. Product Data Sheet
UsesLonzest(R) SMS-20 is used as an emulsifier for plastic & polymers, personal care and industrial applications.
UsesTween 60 is an emulsifier manufactured by reacting stearic acid with sorbitol to yield a product which is reacted with ethylene oxide. It is a nonionic, waterdispersible surface-active agent which is very hydrophilic. It is also termed polysorbate 60. It is used in whipped vegetable toppings for overrun and lightness; in cakes for increased volume and fine grain; in icings and confectionery for lightness and syneresis control; and in salad dressing for emulsion stability. It is frequently used with sorbitan monostearate or monoand diglycerides. The typical usage range is 0.10–0.40%.
Usesazalide antibiotic
DefinitionChEBI: A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a stearate group.
Brand nameTween 60 (ICI Americas).
General DescriptionTWEEN 60 is a niosome.
Flammability and ExplosibilityNonflammable
Safety ProfileModerately toxic by intravenous route. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.
Tween 60 Preparation Products And Raw materials
Raw materialsHydrogen peroxide–>Nitrogen–>ETHYLENE OXIDE–>Sodium ethoxide–>Stearic acid–>Sorbitol–>Span 60
Preparation ProductsSpining lubricant agent

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