| Flufenoxuron Basic information |
| Product Name: | Flufenoxuron |
| Synonyms: | N-[4-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-2-FLUOROPHENYLAMINOCARBONYL]-2,6-DIFLUORO-BENZAMIDE;CASCADE;FLUFENOXURON;N-((4-(2-chloro-4-(triluoromethyl)phenoxy))amino)carbonyl-2,6-difluorobenzamide;FLUFENOXURON PESTANAL, 250 MG;flufenoxoron;(1-(4-(2-chloro-α,α,α-trifluoro-p-tolyloxy)-2-fluorophenyl)-3-(2,6-difluorobenzoyl)urea;Benzamide, N-4-2-chloro-4-(trifluoromethyl)phenoxy-2-fluorophenylaminocarbonyl-2,6-difluoro- |
| CAS: | 101463-69-8 |
| MF: | C21H11ClF6N2O3 |
| MW: | 488.77 |
| EINECS: | 417-680-3 |
| Product Categories: | |
| Mol File: | 101463-69-8.mol |
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| Flufenoxuron Chemical Properties |
| Melting point | 169-172° (dec) |
| density | 1.5123 (estimate) |
| vapor pressure | 6.52 x l0-12 Pa (20 °C) |
| storage temp. | 0-6°C |
| solubility | Benzene (Slightly, Heated), DMSO (Slightly), Ethyl Acetate (Sparingly) |
| Water Solubility | 4 x l0-6 mg l-1(25 °C) |
| pka | 8.68±0.46(Predicted) |
| form | neat |
| color | Off-White to Light Beige |
| BRN | 8398323 |
| CAS DataBase Reference | 101463-69-8(CAS DataBase Reference) |
| EPA Substance Registry System | Flufenoxuron (101463-69-8) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 20 |
| Safety Statements | 22 |
| RIDADR | 3077 |
| WGK Germany | 2 |
| RTECS | CV2474500 |
| HazardClass | 9 |
| PackingGroup | III |
| Hazardous Substances Data | 101463-69-8(Hazardous Substances Data) |
| Toxicity | LD50 in rats (mg/kg): >3000 orally; >2000 percutaneously (Anderson) |
| Flufenoxuron Usage And Synthesis |
| Uses | Flufenoxuron is used for the control of many phytophagous mites (Aculus, Brevipalpus, Pananychus, Phyllocoptuuta, Tetuanychus, spp) and insect pests on pome fruit, vines, citrus, tea, cotton, maize, vegetables and ornamentals. It is also used as a public hygiene insecticide. |
| Uses | Flufenoxuron is an known insecticide and acts as an insect growth regulator by inhibiting chitin synthesis. |
| Definition | ChEBI: Flufenoxuron is a benzoylurea insecticide, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes, a member of monofluorobenzenes and a difluorobenzene. It has a role as a mite growth regulator. It derives from a diphenyl ether. |
| Metabolic pathway | Information on the metabolism of flufenoxuron is avilable in a Pesticides Safety Directorate review of its use as a public hygiene insecticide (PSD). |
| Degradation | The DT50 of flufenoxuron (25 °C) was 267 days at pH 7,206 days at pH 5 and 36.7 days at pH 9 (PM). Flufenoxuron underwent photodegradation to form 2,6-difluorobenzamide (2), the urea derivative 3 and the 4-aminodiphenyl ether 4 in aqueous solution under natural sunlight in the UK (PSD, 1995). |
| Mode of action | Flufenoxuron acts in a similar manner to diflubenzuron, reducing chitin incorporation in the cuticJe (Clarke and Jewess 1990). It has cuticular and stomach action. It has ovo-Iarvicidal activity. Treated adults lay non-viable eggs (Tomlin 1995). |
| Flufenoxuron Preparation Products And Raw materials |
| Raw materials | Oxalyl chloride–>PHOSGENE–>CHLOROETHANE–>Chlorfluazuron–>3,4-Dichlorobenzotrifluoride–>2,6-Difluorobenzamide–>2-Fluoroaniline–>2,6-Difluorobenzoyl isocyanate–>4-Amino-3-fluorophenol |
| Preparation Products | Hexaflumuron |