NADP, Disodium Salt

NADP, Disodium Salt Basic information
Product Name:NADP, Disodium Salt
Synonyms:B-NICOTINAMIDE ADENINE DINUCLEOTIDE 3′-PHOSPHATE, DISODIUM SALT;BETA-NADP-NA2;NADP+, DISODIUM SALT;NADP, OXIDIZED FORM, DISODIUM;NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE DISODIUM SALT;TRIPHOSPHOPYRIDINE NUCLEOTIDE SODIUM SALT;TRIPHOSPHOPYRIDINE NUCLEOTIDE, OXIDIZED FORM, DISODIUM;TPN, 2NA
CAS:24292-60-2
MF:C21H29N7NaO17P3
MW:767.41
EINECS:246-129-8
Product Categories:Bioproducts;Cofactor
Mol File:24292-60-2.mol
NADP, Disodium Salt Structure
NADP, Disodium Salt Chemical Properties
Melting point 175-178 °C
density 1.66g/cm3 at 20℃
vapor pressure 0.002-0.004Pa at 20-25℃
storage temp. -20°C
solubility DMSO (Slightly), Water (Slightly)
form Powder
color Yellow
OdorOdorless
PH4.0 ± 1.0(10mg/mL)
Water Solubility >50 g/L
Stability:Hygroscopic
InChIKeyUNRRSQIQTVFDLS-WUEGHLCSSA-L
LogP-4.4 at 20℃ and pH7
Surface tension73.2mN/m at 1g/L and 20℃
CAS DataBase Reference24292-60-2
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-37/39-36-26
WGK Germany 3
F 10-21
HS Code 29349990
MSDS Information
ProviderLanguage
ACROSEnglish
SigmaAldrichEnglish
NADP, Disodium Salt Usage And Synthesis
DescriptionNADP+ is a coenzyme that is widely distributed in living matter, Participates in oxidation-reduction reactions. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).
NADP is a substance in which nicotinic acid amide adenine dinucleotide and a phosphate molecule are bound by ester bond. It is a hydrogen receptor and can be used for the development and development of a variety of in vitro diagnostic reagents. Prepared in large quantities.
NADP
Chemical PropertiesYellowish powder
UsesNicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.
UsesDisodium NADP is used in method for preparing 2,4-Diamino Butyric Acid by enzyme catalysis.
General DescriptionNicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo.
Mechanism of actionβ-Nicotinamide adenine dinucleotide NAD and β-nicotinamide adenine dinucleotide phosphate NADP are coenzymes necessary for cellular energy metabolism and play a central role in energy metabolism. In addition, purine nucleotides also play an important transfer role in biological processes. Protons in energy reactions are usually first transferred to NAD and NADP, then reduced to NADH and NADPH, and transferred to oxygen through electrons to release energy. The generated reduced NADH and NADPH are coenzymes of glutathione reductase and have important antioxidant functions.
Biotechnological ApplicationsNicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo. The β-NADH phosphate disodium salt has been used for the quantification of glucose in glycogen. It has also been used for the hexokinase assay.
PrecautionsProtect from light and moisture. Keep cool and dry. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Store under inert gas.

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