Piperonyl chloride

Piperonyl chloride Basic information
Product Name:Piperonyl chloride
Synonyms:Piperonyl Chloride (~75% by weight in CH2Cl2);Piperonyl chloride(50% by weight in dichloromethane or dichloroethane);TIMTEC-BB SBB005588;PIPERONYL CHLORIDE;1,3-BENZODIOXOLE, 5-(CHLOROMETHYL)-;5-(CHLOROMETHYL)-1,3-BENZODIOXOLE;4-Chloromethyl-1,2-methylenedioxybenzene;5-(chloromethyl)-3-benzodioxole
CAS:20850-43-5
MF:C8H7ClO2
MW:170.59
EINECS:244-081-2
Product Categories:
Mol File:20850-43-5.mol
Piperonyl chloride Structure
Piperonyl chloride Chemical Properties
Melting point 20.5°C
Boiling point 97-100°C 1mm
density 1.32
refractive index 1.5660 (estimate)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform, Methanol
form Clear Yellow Solution
Sensitive Moisture Sensitive/Lachrymatory
CAS DataBase Reference20850-43-5(CAS DataBase Reference)
NIST Chemistry Reference3,4-Methylenedioxybenzyl chloride(20850-43-5)
EPA Substance Registry System1,3-Benzodioxole, 5-(chloromethyl)- (20850-43-5)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39
Hazard Note Irritant/Lachrymatory/Moisture Sensitive
HazardClass IRRITANT, MOISTURE SENSITIVE, LACHRYMATOR
HS Code 2932990090
MSDS Information
ProviderLanguage
5-(Chloromethyl)-1,3-benzodioxoleEnglish
Piperonyl chloride Usage And Synthesis
Chemical PropertiesClear Yellow Solution
UsesPiperonyl Chloride is used as a reagent in the synthesis of anti-proliferative hydroxyguanidine compounds.
Synthesis Reference(s)Journal of Medicinal Chemistry, 16, p. 869, 1973 DOI: 10.1021/jm00266a001
Piperonyl chloride Preparation Products And Raw materials
Raw materialsCatechol–>1,3-Benzodioxole–>1,3,5-trioxane
Preparation ProductsPIPERONYL ACETATE–>2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine–>5-BROMO-6-(CHLOROMETHYL)-1,3-BENZODIOXOLE

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