| Imidazole-2-carboxaldehyde Basic information |
| Product Name: | Imidazole-2-carboxaldehyde |
| Synonyms: | 2-FORMAYLIMIDAZOLE;Imidazole-2-carboxaldehyde p;Imidazole-2-carboxaldehyde ,98%;Imidazole-2-carboxal;2-AcetliMidazole;2-Formyl-1H-imidazole;2-IMidazolecarboxaldehyde 97%;Imidazole-2-carboxaldehyde,97% |
| CAS: | 10111-08-7 |
| MF: | C4H4N2O |
| MW: | 96.09 |
| EINECS: | 600-165-4 |
| Product Categories: | Imidazoles & Benzimidazoles;Building Blocks;Heterocyclic Building Blocks;Imidazole;Imidazol&Benzimidazole;Imidaxoles;Building Blocks;C1 to C6;Carbonyl Compounds;Chemical Synthesis;Heterocyclic Building Blocks;Organic Building Blocks;Aldehydes;blocks;Imidazoles;Imidazoles & Benzimidazoles |
| Mol File: | 10111-08-7.mol |
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| Imidazole-2-carboxaldehyde Chemical Properties |
| Melting point | 209 °C (dec.) (lit.) |
| Boiling point | 296.5±23.0 °C(Predicted) |
| density | 1.322±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Sparingly), Methanol (Slightly, Sonicated) |
| form | Solid |
| pka | 11.48±0.10(Predicted) |
| color | Light Brown to Brown |
| Water Solubility | Soluble in water. |
| Sensitive | Air Sensitive |
| BRN | 4371302 |
| InChIKey | XYHKNCXZYYTLRG-UHFFFAOYSA-N |
| CAS DataBase Reference | 10111-08-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 1H-imidazole-2-carboxaldehyde(10111-08-7) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-36/37/39-3 |
| WGK Germany | 3 |
| F | 10 |
| HazardClass | IRRITANT |
| HS Code | 29332900 |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ALFA | English |
| Imidazole-2-carboxaldehyde Usage And Synthesis |
| Chemical Properties | White to light brown solid |
| Uses | 1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes. |
| Uses | Used in a study of the imidazole-directed allylation of aldimines.1 |
| Uses | Imidazole-2-carboxaldehyde is a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor with an important application to treat type-2 diabetes. It is used in the preparation of tridentate Schiff-base carboxylate-containing ligands by undergoing condensation reaction with amino acids beta-alanine and 2-aminobenzoic acid. It is also involved in the study of the imidazole-directed allylation of aldimines. |
| Synthesis Reference(s) | Organic Syntheses, Coll. Vol. 7, p. 287, 1990 The Journal of Organic Chemistry, 60, p. 1090, 1995 DOI: 10.1021/jo00109a052 |
| Imidazole-2-carboxaldehyde Preparation Products And Raw materials |